Sepsis Now Part of CMS Value-Based Purchasing Program SUMMARY The U.S. Center for Medicare and Medicaid Services (CMS) Severe Sepsis and Septic Shock Early Management Bundle (SEP-1) lays out the process for providers to follow in the care of the sepsis patient. First published in 2015, then amended in 2018, CMS is
Machine Learning Predictive Spesis Models SUMMARYVarious machine learning sepsis prediction models exist and are promoted to facilitate early identification of patients at high risk for sepsis.Most are based on electronic health record data.Results range from producing improvements in outcomes to poor discrimination and calibration with poor predictability of sepsis onset and no
The Neurologic Complications of Sepsis SUMMARY Nervous system manifestations are often the first sign of organ failure to occur in sepsis. There are a wide range of clinical syndromes including confusion, seizures, and cerebrovascular events. The 2 most common are Sepsis associated encephalopathy and ICU acquired weakness. Current diagnostic and management strategies
Early Restrictive or Liberal Fluid Management for Sepsis: The CLOVERS Study SUMMARY Complete fluid resuscitation should consider macrovascular perfusion as well as microvascular perfusion. There is a lack of data to adequately guide clinicians on fluid and vasopressor use in early sepsis. The CLOVERS study suggests restrictive fluid with early
Rethinking IV Fluid Resuscitation in Sepsis SUMMARY Fluid resuscitation is a key component in the management of sepsis and shock to improve fluid volume. The risks of fluid overload may contribute to poorer outcomes. Despite widespread support for fluid resuscitation, data supporting large volumes is limited. REVIEW The Surviving Sepsis Campaign recommends
Sepsis Performance Programs Can Optimize Patient Outcomes SUMMARY Sepsis performance improvement programs can optimize compliance with sepsis protocols and are associated with improved patient outcomes. Having a Sepsis Performance Improvement program is more important than the specific content of the program. Engaging a large multidisciplinary group of clinical leaders is
Sepsis Mortality Based on Origin of Source SUMMARY Sepsis sources of infection come from a variety of origins. Source control is a major determinant affecting outcomes in patients with sepsis. The source of the sepsis origin may partially contribute to varying mortality rates. Infection source should be considered in sepsis
Source Control in the Management of Sepsis SUMMARY Source control is a major determinant affecting outcomes in patients with sepsis. The need for source control should be linked into the diagnostic process of sepsis patients. Source control should be considered in every sepsis patient, but it may not be necessary to control
3 Key Factors for an Effective Sepsis Performance Improvement Program SUMMARYThere are several components to an effective sepsis performance improvement program.Having a sepsis performance improvement program in itself maybe more important than the specific content, there are a few mandatory components required for effectiveness.Including a large multidisciplinary clinical group is also essential
Hospital Cost of Sepsis Around the World SUMMARY Sepsis remains one of the costliest hospital conditions. Globally, average total hospital costs per patient varies greatly from €1,101 to €91,951. The healthcare budget by country spent of sepsis also varied dramatically based on % of GDP. REVIEW Despite being the most frequent and
