About Erkan Hassan, PharmD

Erkan has over 20 years’ experience solving clinical challenges and improving patient-centered outcomes by using evidence-based clinical data to create innovative, intelligent healthcare systems. This consists of proactive clinical surveillance, streamlining workflows, measuring and reporting outcomes.

Should Hemodynamic Profiling be a Sepsis Best Practice?

By |2021-10-18T07:35:40+00:00October 18th, 2021|Sepsis|

Should Hemodynamic Profiling be a Sepsis Best Practice? SUMMARY Hemodynamic profiles in critically ill patients are complex and change over the sepsis course. Macro-circulatory and micro-circulatory factors contribute equally to the evolving disease state. During the later stages of hemodynamic impairment, both factors must be considered. BACKGROUNDIn addition to

Sepsis Associated Encephalopathy (SAE)

By |2021-09-21T03:43:48+00:00September 21st, 2021|Sepsis|

Sepsis Associated Encephalopathy (SAE) SUMMARYSAE is a key manifestation of sepsis occurring in up to 70% of ICU patientsAssociated with higher ICU and hospital mortality and long term consequencesDifficult to assess, diagnose without specific treatment BACKGROUNDSAE is probably the most common type of encephalopathy in the ICUSAE may occur

Is the Mortality Rate from Sepsis Improving?

By |2021-08-25T08:55:11+00:00August 25th, 2021|Sepsis|

Is the Mortality Rate from Sepsis Improving? SUMMARY The true incidence of sepsis is difficult to define. Sepsis cases are not evenly distributed Despite global efforts on improved recognition and management, the overall sepsis mortality rate has been stable. Sub-segments of the population may be experiencing increasing mortality rates. BACKGROUND

What Truly Defines Organ Dysfunction Due to Sepsis?

By |2021-08-09T06:40:35+00:00August 9th, 2021|Sepsis|

How Should We Screen for Sepsis? SUMMARY Organ dysfunction is one of the defining characteristics in the current definition of sepsis. Many of the markers currently in use are nonspecific. Organ dysfunction and injury are separate processes that need to be differentiated. Understanding ways dysfunction can be better detected will

How Should We Screen for Sepsis?

By |2021-07-26T08:49:55+00:00July 26th, 2021|Sepsis|

How Should We Screen for Sepsis? SUMMARY Sepsis screening remains a major challenge, especially in varied settings. Effective screening impacts treatment, quality of care initiatives and outcomes. Different screening tools may be needed based on the clinical setting. The tool at each site may need to be tuned uniquely for that population

Optimal Modes of Sepsis Care Delivery

By |2021-07-12T09:17:45+00:00July 12th, 2021|Sepsis|

Optimal Modes of Sepsis Care Delivery SUMMARY The 2016 Surviving Sepsis Campaign guidelines (Sepsis-3) provided a new definition for sepsis, but also raised new questions. Recently the Sepsis-3 Research Committee listed priorities for further consideration. The only area focusing on sepsis administrative issues was on the optimal mode of care delivery. REVIEW

5 Tips with Electronic Sepsis Notification Systems

By |2021-06-30T04:48:49+00:00June 30th, 2021|Sepsis|

5 Tips with Electronic Sepsis Notification Systems Numerous studies have developed electronic tools for the detection of sepsis. As machine learning evolves, many more will probably abound. Most evaluations are fraught with methodologic design pitfalls which preclude widespread implementation and use for patient identification and improved clinical outcomes. The following

Carbapenem Resistant Gram Negative Bacilli

By |2021-06-24T06:04:39+00:00June 14th, 2021|Sepsis|

Carbapenem Resistant Gram Negative Bacilli SUMMARY The continued growth of multidrug resistant organisms, particularly carbapenem resistant Gram negative rods, places a heavy burden on the healthcare system globally Effective treatment regimens remain a challenge. Although combination therapy is typically used, robust evidence to support this strategy is lacking. There are

Sepsis Associated Acute Kidney Injury: Knowns and Unknowns

By |2021-06-24T07:05:32+00:00May 26th, 2021|Sepsis|

Sepsis Associated Acute Kidney Injury: Knowns and Unknowns SUMMARY By the time patients seek attention, most have already developed acute kidney injury. Sepsis associated acute kidney injury is a distinct syndrome different from other non-sepsis acute kidney injuries. There is a lack of specific interventions for the prevention and treatment

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