Can Progression from Sepsis to Septic Shock be Predicted? SUMMARY Approximately 10% of patients with sepsis will progress to septic shock. Septic Shock is associated with a high mortality rate of approximately 38%. Limited data exists determining which patients

Optimal Antimicrobial Treatment Duration in Sepsis SUMMARY There is limited guidance on the optimal duration of antimicrobial therapy for sepsis patients. Prolonged courses in severely ill patients is a common occurrence. With a lack of data, clinicians are left

Evaluation of Risk Adjustment on Hospital Sepsis Mortality SUMMARY The lack of a validated sepsis risk adjustment tool does not allow for a comparison of clinical outcomes across sites. Risk adjustment allows the evaluation of additional improvements such as

Association Between Temperature and Sepsis Mortality SUMMARY Temperature is an important determinant in sepsis patients. Hyperthermia is not the sole factor impacting outcomes. Hypothermia as well as normothermia contribute to poorer outcomes and need to be considered in any

The Impact of Nursing Resources on Sepsis Outcomes SUMMARY Nurses play an important role in effective sepsis identification and management. The level of nursing resources varies across hospitals, with better resourced hospitals demonstrating improved clinical and economic sepsis outcomes.

The Uncertain Optimal Time for Antibiotics in Sepsis SUMMARY Most sepsis treatment protocols call for antibiotic administration as soon as possible. This practice may benefit patients with septic shock, it may be detrimental for those without shock. Forcing clinicians