Should Hemodynamic Profiling be a Sepsis Best Practice? SUMMARY Hemodynamic profiles in critically ill patients are complex and change over the sepsis course. Macro-circulatory and micro-circulatory factors contribute equally to the evolving disease state. During the later

Sepsis Associated Encephalopathy (SAE) SUMMARYSAE is a key manifestation of sepsis occurring in up to 70% of ICU patientsAssociated with higher ICU and hospital mortality and long term consequencesDifficult to assess, diagnose without specific treatment

Top 10 Key Perspectives for Sepsis in 2022 SUMMARY The challenge of sepsis remains for most clinicians There is no one-size fits all approach Several unresolved key areas will remain with us into the next year

Is the Mortality Rate from Sepsis Improving? SUMMARY The true incidence of sepsis is difficult to define. Sepsis cases are not evenly distributed Despite global efforts on improved recognition and management, the overall sepsis mortality

How Should We Screen for Sepsis? SUMMARY Organ dysfunction is one of the defining characteristics in the current definition of sepsis. Many of the markers currently in use are nonspecific. Organ dysfunction and injury are

How Should We Screen for Sepsis? SUMMARY Sepsis screening remains a major challenge, especially in varied settings. Effective screening impacts treatment, quality of care initiatives and outcomes. Different screening tools may be needed based on the clinical