Two Standards of Sepsis Care - The Nighttime Effect SUMMARY Services in most hospitals differ between day & night or weekend shifts. With clinical staff and hospital resources typically diminished during "off hours", there is increased risk

Sepsis on the Basis of Suspicion of Infection SUMMARY A suspected or documented infection is required for the diagnosis of sepsis. The lack of a “gold standard” for sepsis diagnosis coupled with the delay of culture results

Changes in Sepsis Trends: Real or Artificial? SUMMARY Recent reports indicate a significant increase in the incidence of sepsis with a concomitant drop in mortality. Controversy exists over the true degree of change based on

Use of Steroids in Sepsis SUMMARY The use of corticosteroids in sepsis has been recommended on and off for over 40 years. The Surviving Sepsis Campaign (SSC) guidelines previously (2016) did not support steroid use in patients

3 Major Lactate Considerations in Sepsis SUMMARY Serum lactate measurements have been part of the sepsis bundles since the beginning. The recommendation to use and follow serum lactate concentrations are based on weak and low-quality evidence. Changes

Should Hemodynamic Profiling be a Sepsis Best Practice? SUMMARY Surviving Sepsis Campaign (SSC) guidelines were previously developed in 2016 and published in 2017. The SSC 2021 guidelines provides an update to the SSC 2016 guidelines. New