Carbapenem Resistant Gram Negative Bacilli SUMMARY The continued growth of multidrug resistant organisms, particularly carbapenem resistant Gram negative rods, places a heavy burden on the healthcare system globally Effective treatment regimens remain a challenge. Although

Sepsis Associated Acute Kidney Injury: Knowns and Unknowns SUMMARY By the time patients seek attention, most have already developed acute kidney injury. Sepsis associated acute kidney injury is a distinct syndrome different from other non-sepsis acute

Will Improving CMS SEP-1 Metrics Correlatewith Sepsis Clinical Outcomes?  SUMMARY CMS SEP-1 quality metrics can consume large amounts of hospital resources in order to collect and report their adherence. Hospitals solely focusing on the SEP-1 reporting

Components of Timely Antibiotic Administration in Sepsis SUMMARY There are at least 2 components to consider in timely antibiotic use in sepsis patients. The time from triage to ordering antibiotics caused four-fifths of the delay in

The Confusing State of Sepsis Definition SUMMARY There is large variability in incidence and clinical outcome (including mortality) in sepsis patients based on the definition used. The differing definitions make it difficult for providers and health systems to: Evaluate outcomes

Low Agreement in Sepsis Time-Zero DeterminationSUMMARYVariability in time-zero determination may limit the interpretation of pass/fail sepsis bundle compliance.Three different definitions exist to meet time-zero criteria.There is wide variability between clinicians and abstractors in determining time-zero with poor interrater reliability.