Heart Rate & Temperature as Sepsis Mortality Prognostic Indicator SUMMARY The systemic effects of sepsis are due to the activation of a variety of physiologic cascades. Activation of the sympathetic nervous system with catecholamine release
Sepsis Associated Kidney Injury in the ICU SUMMARY Acute Kidney Injury often times accompanies sepsis. Sepsis Associated Acute Kidney Injury (SA-AKI) has a greater morbidity and mortality rate than sepsis or acute kidney injury alone.
Use of Machine Learning Algorithms in Sepsis SUMMARY The predictive value of sepsis clinical scoring systems is controversial but needs further improvement. Machine learning methods have recently emerged in the use of predicting disease identification,
Prolonged vs Intermittent Antibiotic Infusions SUMMARYRecent efforts to maximize antibiotic activity have focused on using pharmacokinetic (PK) and pharmacodynamic (PD) principles for drug administration.As a preferred choice, beta lactams, and specifically meropenem displays a time dependent
Centers for Disease Control and Prevention Sepsis Initiatives SUMMARY The U.S. Centers for Disease Control and Prevention (CDC) has proposed the “Adult Sepsis Event Toolkit” - 2018 (ASE Toolkit), and the “Hospital Sepsis Program Core
Socioeconomic Impact on Sepsis SUMMARYSocioeconomic variables, beyond the control of patients and providers can impact the outcomes of sepsis patients.Larger data sets are needed to confirm the full impact of socioeconomic factors on sepsis mortality and hospital