Diagnostic Challenges in Sepsis SUMMARY There remains no single tool to reliably identify sepsis. A variety of approaches exist as well as on the horizon in order to identify infection and sepsis. Identification must bridge the

Two Standards of Sepsis Care - The Nighttime Effect SUMMARYQuick Sequential Organ Failure Assessment (qSOFA) has not provided the high predictive performance initially proposed.Modifications to qSOFA has been investigated as a way to improve performance, especially

Two Standards of Sepsis Care - The Nighttime Effect SUMMARY Services in most hospitals differ between day & night or weekend shifts. With clinical staff and hospital resources typically diminished during "off hours", there is increased risk

Sepsis on the Basis of Suspicion of Infection SUMMARY A suspected or documented infection is required for the diagnosis of sepsis. The lack of a “gold standard” for sepsis diagnosis coupled with the delay of culture results

Changes in Sepsis Trends: Real or Artificial? SUMMARY Recent reports indicate a significant increase in the incidence of sepsis with a concomitant drop in mortality. Controversy exists over the true degree of change based on

Use of Steroids in Sepsis SUMMARY The use of corticosteroids in sepsis has been recommended on and off for over 40 years. The Surviving Sepsis Campaign (SSC) guidelines previously (2016) did not support steroid use in patients