3 Greatest Barriers and Approaches to Sepsis Program Implementations SUMMARY Implementation of an effective sepsis program is both time consuming and complicated. Each institution poses its own unique challenges. Despite this wide heterogeneity, 3 major common themes

Is Time to Antibiotics a Good Metric for Sepsis? SUMMARY Optimal antibiotic timing remains an actively debated topic. Sepsis is an extremely heterogeneous syndrome, therefore, with which characteristics do earlier antibiotic administration improve outcomes? A more

Diagnostic Challenges in Sepsis SUMMARY There remains no single tool to reliably identify sepsis. A variety of approaches exist as well as on the horizon in order to identify infection and sepsis. Identification must bridge the

Two Standards of Sepsis Care - The Nighttime Effect SUMMARYQuick Sequential Organ Failure Assessment (qSOFA) has not provided the high predictive performance initially proposed.Modifications to qSOFA has been investigated as a way to improve performance, especially

Two Standards of Sepsis Care - The Nighttime Effect SUMMARY Services in most hospitals differ between day & night or weekend shifts. With clinical staff and hospital resources typically diminished during "off hours", there is increased risk

Sepsis on the Basis of Suspicion of Infection SUMMARY A suspected or documented infection is required for the diagnosis of sepsis. The lack of a “gold standard” for sepsis diagnosis coupled with the delay of culture results