A recent retrospective review from the University of Pittsburgh Medical Center (UPMC) reviewed data form January 2013 through December 2017.
The goal was to determine what association, if any, existed between the implementation of the CMS SEP-1 quality metrics and sepsis treatments and outcomes.
Analysis from 11 hospitals in:
- 54,225 ED patient encounters with community onset sepsis only
- 29,051 patients PRE-SEP-1 Initiation
- 22,759 patients POST SEP-1 initiation
- 2,415 patients were excluded during the first quarter of SEP-1 initiation as a “washout period” (October 2015 – December 2015).
The UPMC assessment model calculated and compared an “expected” value for each outcome to the actual value in order to account for inherent changes in hospitals over time.
PRE & POST SEP-1 findings were:
- A significant improvement in lactate measurement, antibiotic administration and fluid administration occurred.
- The largest improvement was in lactate measurements
- There was a lack in any significant or clinically meaningful improvement in clinical outcomes in the total population or subgroups.