The Health Burden of Sepsis After Hospitalization
- A number of health complications are known to develop after an episode of sepsis referred to as the “Post-Sepsis Syndrome”
- There is inconclusive data if the syndrome is attributable to the sepsis episode or pre-existing co-morbidities.
- Increased risk of mortality, readmission, length of stay, cost of care, cognitive impairment and cardiovascular events have all been included in the Post-Sepsis Syndrome.
The risk factors for the systemic inflammatory response, the immune response and organ dysfunction associated with sepsis are not completely understood.
In addition to the short term morbidity and mortality these risk factors may impact, they may also influence the development of a number of long term health complications post-sepsis referred to as “Post-Sepsis Syndrome”.
There is a growing body of literature evaluating the various late complications associated with the Post-Sepsis Syndrome. Due to this limited amount of data coupled with study design, we can only make inferences about a causal link and magnitude between sepsis and post-acute morbidity and mortality.