Early Restrictive or Liberal Fluid Management for Sepsis: The CLOVERS Study SUMMARY Complete fluid resuscitation should consider macrovascular perfusion as well as microvascular perfusion. There is a lack of data to adequately guide clinicians on fluid and vasopressor use in early sepsis. The CLOVERS study suggests restrictive fluid with early
Rethinking IV Fluid Resuscitation in Sepsis SUMMARY Fluid resuscitation is a key component in the management of sepsis and shock to improve fluid volume. The risks of fluid overload may contribute to poorer outcomes. Despite widespread support for fluid resuscitation, data supporting large volumes is limited. REVIEW The Surviving Sepsis Campaign recommends
Sepsis Performance Programs Can Optimize Patient Outcomes SUMMARY Sepsis performance improvement programs can optimize compliance with sepsis protocols and are associated with improved patient outcomes. Having a Sepsis Performance Improvement program is more important than the specific content of the program. Engaging a large multidisciplinary group of clinical leaders is
Sepsis Mortality Based on Origin of Source SUMMARY Sepsis sources of infection come from a variety of origins. Source control is a major determinant affecting outcomes in patients with sepsis. The source of the sepsis origin may partially contribute to varying mortality rates. Infection source should be considered in sepsis
Source Control in the Management of Sepsis SUMMARY Source control is a major determinant affecting outcomes in patients with sepsis. The need for source control should be linked into the diagnostic process of sepsis patients. Source control should be considered in every sepsis patient, but it may not be necessary to control
3 Key Factors for an Effective Sepsis Performance Improvement Program SUMMARYThere are several components to an effective sepsis performance improvement program.Having a sepsis performance improvement program in itself maybe more important than the specific content, there are a few mandatory components required for effectiveness.Including a large multidisciplinary clinical group is also essential
Hospital Cost of Sepsis Around the World SUMMARY Sepsis remains one of the costliest hospital conditions. Globally, average total hospital costs per patient varies greatly from €1,101 to €91,951. The healthcare budget by country spent of sepsis also varied dramatically based on % of GDP. REVIEW Despite being the most frequent and
3 Key Factors When Using Hospital Sepsis Discharge Data SUMMARYHospital discharge data is easy to obtain but may be misleading due to:Lack of clinical dataSubject to documentation limitationsVarious identification strategies have been developedConversion from ICD-9 to ICD-10 has expanded sepsis coding options resulting in different incidence rates and patterns.REVIEWChan et al JACEP
Potential Value of Point-of-Care Testing in Improving Outpatient Sepsis BACKGROUND General practitioners are typically the first health care provider assessing patients with acute infections. This applies to sepsis cases as well Most sepsis cases begin outside the hospital: 75% of all sepsis patients admitted to the hospital were at home 4
3 Greatest Barriers and Approaches to Sepsis Program Implementations SUMMARY Implementation of an effective sepsis program is both time consuming and complicated. Each institution poses its own unique challenges. Despite this wide heterogeneity, 3 major common themes are the cause of much difficulty and confusion. The key to success in sepsis program
