Sepsis Mortality Based on Origin of Source
- Sepsis sources of infection come from a variety of origins.
- Source control is a major determinant affecting outcomes in patients with sepsis.
- The source of the sepsis origin may partially contribute to varying mortality rates.
- Infection source should be considered in sepsis program development.
- Due to the heterogeneous nature of sepsis, a variety of sources may be the origin of the infection.
- Consistently, the most common source origin is the pulmonary system. However, clinicians also need to consider a number of other sites.
- Recently Prest et al evaluated sepsis patients stratified by the 3 most common sites of infection in over 2.5 million sepsis cases reported through the CDC.
- Genitourinary tract
- Pulmonary sepsis patients had the highest mortality rate, followed by GU sepsis, then Intrabdominal sepsis.
- Males had a significantly higher mortality rate (approximately 26% higher age-adjusted) than females within each source origin.
- Sepsis mortality increase not only by organ system affected, but by increasing age as well.
- Pulmonary remained the leading cause of death by age group as well.
- The site of infection origin is important ot consider in the effort to combat sepsis.
- The organ affected as well as the patients age should be factors to consider in developing sepsis processes and policies.
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Erkan Hassan is the Co-Founder & Chief Clinical Officer of Sepsis Program Optimization where he designs & oversees the implementation of solutions to optimize sepsis programs.
To discuss your organization’s Barriers of Effective Sepsis Care, contact Erkan by phone (844) 4SEPSIS (844-473-7747), email (firstname.lastname@example.org), or video chat.